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SecA – SecYEG DIBMA nanodisc protocol

 SecY is the main transmembrane subunit of the bacterial Sec pathway and a protein-secreting ATPase complex. Homologs of the SecYEG complex are found in eukaryotes and in archaea. SecA is a cell membrane associated subunit. Within this system the SecA ATPase forms a translocase complex with the SecYEG channel, thereby driving the movement of the protein substrate across the membrane.

The two attached documents investigate this interaction via labeling of SecA (MOX-P-112) and SecYEG  (MOX-P-113), respectively.

protein – protein | membrane protein | nanodisc | MOX-P-112 | MOX-P-113

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