Methanosarcina mazei is a model organism for methanoarchaea growing under strictly anaerobic conditions. Next to regulatory proteins, also small noncoding RNAs (sRNAs) are involved in nitrogen (N)-regulation, such as sRNA₄₁, which is highly expressed under N-sufficiency. One of its targets is ‘5’UTR MM2089 mRNA, a polycistronic mRNA encoding for acetyl-CoA-decarbonylase/synthase complexes (ACDS).

RNA – RNA interaction | Nitrogen (N)-regulation | MO-P-026