Mitogen-activated protein kinase 14 (also called p38-α) is an enzyme that has been implicated in the regulation of many proinflammatory pathways. It is a drug target for many diseases such as rheumatoid arthritis, endotoxic shock and osteoporosis. SB 203580 is a specific and potent inhibitor of kinases that binds p38-α with nM affinity. 

protein – small molecule | kinase | inhibitor | His-tag | MO-P-001