Slow Kinetics Analysis is a cloud-based application available on the NanoTemper Hub. It is designed to help scientists further evaluate Slow Kinetics data generated on Dianthus α, giving researchers a dedicated analytical environment to characterize complex binding interactions that unfold over extended timescales.

What Does the Slow Kinetics Analysis App Do?

The Slow Kinetics Analysis application on NanoTemper Hub ingests raw Slow Kinetics data from Dianthus α, processes the binding traces, and delivers structured analytical outputs tailored to three distinct interaction types:

• Tight binding interactions — for high-affinity, non-covalent interactions where equilibrium is reached slowly

• Covalent inhibitors — for compounds that form an irreversible bond with their target following initial non-covalent binding

• Slow dissociation events — for compounds with prolonged target engagement, characterized either through calculation or via a displacement experiment

A detailed guide on the App usage can be found in Software Workflow - Slow Kinetics.

How to Access the Slow Kinetics Analysis App

Slow Kinetics Analysis access is available for Dianthus alpha instruments with the Slow Kinetics feature enabled. For more information about purchase options for Slow Kinetics, please contact our specialists.

If you have already acquired the Slow Kinetics feature and require access to Slow Kinetics Analysis on the NanoTemper Hub, please reach out to us at support@nanotempertech.com and state the device's serial number (e.g DI-00123).