Ligand category

In DI.Screening Analysis, ligands are automatically assigned to a category depending on the data obtained for a particular ligand. The two main categories, Hits, and Non-Binders, are assigned based on measured Response Amplitude. However, data obtained by Dianthus instruments can contain other interesting information about a ligand. For example, if a ligand shows autofluorescence or induces target aggregation. Here are the ligand categories in Single-Dose Screening and Affinity Screening:

 

 

DI.Screening Analysis software also shows a pie chart with the ligand categories on the summary page:

 

 

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