Isothermal denaturation of p38-alpha protocol
Mitogen-activated protein kinase 14 (also called p38-α) is an enzyme that has been implicated in the regulation of many proinflammatory pathways. It is a drug target for many diseases. Kinetic analysis of the thermal stability of p38-α can be used for activation energy analysis and long-term stability prediction.
thermal unfolding | unfolding kinetics | isothermal | Arrhenius equation | activation energy |PR-P-004